Arrhythmogenicity of Anti-Ro/SSA Antibodies in Patients With Torsades de Pointes
نویسندگان
چکیده
منابع مشابه
Arrhythmogenicity of Anti-Ro/SSA Antibodies in Patients With Torsades de Pointes.
BACKGROUND In patients with autoimmune disease, anti-Ro/SSA antibodies (anti-Ro/SSA) are responsible for a novel autoimmune-associated long-QT syndrome by targeting the hERG potassium channel and inhibiting the related current (IKr). Because anti-Ro/SSA are also present in a significant proportion of healthy subjects and may be associated with torsades de pointes (TdP) arrhythmia, we tested the...
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ژورنال
عنوان ژورنال: Circulation: Arrhythmia and Electrophysiology
سال: 2016
ISSN: 1941-3149,1941-3084
DOI: 10.1161/circep.115.003419